Physiology MCQ 0002

Sertoli cells in the testis have receptors for:

1. FSH
2. LH
3. Inhibin
4. Testosterone

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The Correct option is A

Explanation with High Yield Facts:

• Sertoli cell (a kind of sustentacular cell) is a 'nurse' cell of the testes which is part of a seminiferous tubule. It is activated by follicle-stimulating hormone, and has FSH-receptor on its membranes. FSH binds to Sertoli cells stimulate testicular fluid production and synthesis of intracellular androgen receptor proteins. Sertoli cells secrete anti- mullerian hormone and activins also.
• LH binds to receptors on interstitial cells of Leydig and stimulates testosterone production, which in turn binds to Sertoli cells to promote spermatogenesis.
• Inhibin is a hormone that inhibits FSH production. It is secreted from the Sertoli cells, located in the seminiferous tubule inside the testes.

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