Histology MCQ 0003

Basement membrane consists of all except:

1. Laminin
2. Nidogenin
3. Entactin
4. Rhodopsin

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The Correct option is D

Explanation with High Yield Facts :

• Rhodopsin is present in the retinal rods
• The basement membrane consists of an electron-dense membrane called the lamina densa, about 30–70 nanometres in thickness, and an underlying network of reticular collagen (type IV) fibrils (its precursor is fibroblasts) which average 30 nanometres in diameter and 0.1–2 micrometers in thickness.
• This type IV collagen is of the reticular type, in contrast to the fibrillar collagen found in the interstitial matrix.
• The Lamina Densa (which is made up of type IV collagen fibres; perlecan (a heparan sulfate proteoglycan) coats these fibres and the Lamina Lucida (made up of laminin, integrins, entactins, and dystroglycans) together make up the basal lamina.
• Lamina Reticular is attached to basal lamina with anchoring fibrils (type VII collagen fibres) and microfibrils (fibrilin) is collectively known as the basement membrane.

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